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In contrast to the placebo-treated subjects who experienced minimal changes in body weight over the 16-week treatment period, the pramlintide-treated subjects attained significant weight loss from baseline as early as week 2, which was progressive up to week 16, with no evidence of a plateau

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Transferring the lozenge from one side of the mouth to the other to prevent the onset of soreness can minimize these incidents

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It is recommended to bring water, sunscreen, a hat and comfortable shoes, since the tour involves walking for several hours